Publications

LP2, the first lanthipeptide GPCR agonist in a human pharmacokinetics and safety study

Namsolleck P, Richardson A, Moll GN, Mescheder A. Peptides 136, 170468
Biosynthesis of lanthionine-constrained agonists of G protein-coupled receptors.

Moll GN, Kuipers A, Rink R, Bosma T, de Vries L, Namsolleck P. Biochem Soc Trans. 48, 2195-2203
Does activation of the protective Renin-Angiotensin System have therapeutic potential in COVID-19?

Namsolleck P, Moll GN. Mol Med. 26, 80
High-Throughput Screening for Substrate Specificity-Adapted Mutants of the Nisin Dehydratase NisB.

Zhao X, Cebrián R, Fu Y, Rink R, Bosma T, Moll GN, Kuipers OP. ACS Synth Biol. 9, 1468-1478
Cyclic angiotensin-(1-7) contributes to rehabilitation of animal performance in a rat model of cerebral stroke.

Kuipers, A., Moll, G.N., Levy, A., Krakovsky, M., Franklin, R. Peptides 123, 170193

Genetically Encoded Libraries of Constrained Peptides.

Bosma, T., Rink, R., Moosmeier, M.A., Moll, G.N. Chembiochem 20, 1754-1758
Efficacy of lanthionine-stabilized angiotensin-(1-7) in type I and type II diabetes mouse models.

Kuipers A, Moll GN, Wagner E, Franklin R. Peptides. 112, 78-84

Mechanistic aspects of lanthipeptide leaders.

Plat, A., Kuipers, A., Rink, R., Moll, G.N. Curr. Protein Pept. Sci. 14, 85-96.
Phage display and selection of lanthipeptides on the carboxy-terminus of the gene-3 minor coat protein.

Urban J.U., Moosmeier, M.A., Aumüller, T., Thein, M., Bosma, T., Rink, R., Groth, K., Zulley, M., Siegers, K., Tissot, K., Moll, G.N., Prassler, J.Nature Comm. 2017 Nov 15;8(1):1500
Semi-microbiological synthesis of an active lysinoalanine-bridged analog of glucagon-like-peptide-1.

Kuipers, A., de Vries, L., de Vries, M.P., Rink, R., Bosma, T., Moll, G.N. Peptides 91, 33-39.
Mutagenesis of nisin's leader peptide proline strongly modulates export of precursor nisin.

Plat, A., Kuipers, A., Crabb, J., Rink, R., Moll, G.N. Antonie Van Leeuwenhoek 110, 321-330.

GRPR-selective PET imaging of prostate cancer using [(18)F]-lanthionine-bombesin analogs.

Carlucci, G., Kuipers, A., Ananias, H.J., de Paula Faria, D., Dierckx, R.A., Helfrich, W., Rink, R., Moll, G.N., de Jong IJ, Elsinga PH. Peptides 67, 45-54.

Agonists of MAS oncogene and angiotensin II type 2 receptors attenuate cardiopulmonary disease in rats with neonatal hyperoxia-induced lung injury.

Wagenaar, G.T., Laghmani, E.H., Fidder, M., Sengers, R.M., de Visser, Y.P., de Vries, L., Rink, R., Roks, A,J., Folkerts, G., Walther, F.J.
The effect of the thioether-bridged, stabilized Angiotensin-(1-7) analogue cyclic ang-(1-7) on cardiac remodeling and endothelial function in rats with myocardial infarction.

Durik, M., van Veghel, R., Kuipers, A., Rink, R, Haas, Jimoh Akanbi, M., Moll, G., Danser, A.H., Roks, A.J. Int J Hypertens 2012, 536426.

Bacterial display and screening of posttranslationally thioether-stabilized peptides.

Bosma, T., Kuipers, A., Bulten, E., de Vries, L., Rink, R., Moll, G.N. Appl. Environ. Microbiol. 77, 6794-801.

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